cubeTMF by CRScube: Centralized eTMF That Keeps Studies Inspection-Ready
cubeTMF from CRScube is a centralized electronic Trial Master File solution that helps sponsors, CROs, and investigational sites manage trial documentation with greater clarity and control. By bringing document oversight, quality checks, signatures, and audit trails into one place, teams can reduce manual effort and maintain inspection readiness across the study lifecycle.
Efficient document management
cubeTMF helps teams organize, track, and retrieve trial documents in one place, with support for bulk handling and clear folder structures. This makes day-to-day document management easier across studies, teams, and sites.
Real-time document oversight
Teams can monitor missing or overdue documents using visual indicators, task lists, and status views that help keep TMF activity current and easier to follow.
Audit and inspection readiness
cubeTMF supports quality checks, review processes, electronic signatures, and full audit trails, maintaining the traceability and control expected by regulatory agencies.
Cross-functional collaboration
Sponsors, CROs, and sites can work from the same document environment with shared visibility into current files, updates, and progress. cubeTMF also supports Site Master File management to help site teams collaborate more effectively.
Connected clinical technology
cubeTMF works alongside cubeCONSENT and cubeCTMS as part of the CRScube clinical technology ecosystem, supporting a more unified approach to oversight, documentation, and trial operations.
See It In Action
Read the CRScube case study on how Linical unified clinical trial documentation management with cubeTMF.
Upholding the Highest Compliance Standards
Contact us for an introduction to the Mednet and CRScube eClinical ecosystem with solutions to support all study types and phases.
How does cubeTMF support inspection-readiness?
cubeTMF helps teams maintain clearer control over document completeness, review status, signatures, and audit history. With missing or overdue items easier to identify, teams can keep the Trial Master File current and better prepared for audits and inspections.
Does cubeTMF support document review, quality checks, and signatures?
Yes. cubeTMF supports configurable review workflows, quality checks, and electronic signatures, helping teams manage document control in a more consistent and traceable way.
Can sponsors, CROs, and sites work together in cubeTMF?
Yes. cubeTMF is designed to support collaboration across sponsor and CRO study teams, with shared visibility into current documents, updates, and progress. It also supports Site Master File management to help site teams work more effectively.
How does cubeTMF help teams manage document completeness?
cubeTMF gives teams a clearer view of missing, overdue, and in-progress documents through visual indicators, task lists, and status tracking. This makes it easier to follow up on outstanding items and maintain a more complete TMF.
How does cubeTMF fit within the wider CRScube ecosystem?
cubeTMF works alongside cubeCONSENT and cubeCTMS as part of the CRScube clinical technology ecosystem, helping connect documentation, study oversight, and operational workflows more closely.
What type of teams benefit most from cubeTMF?
cubeTMF is a strong fit for sponsor and CRO study teams that need stronger control over trial documentation, better visibility into TMF status, and a more consistent way to manage review and signature workflows across studies.